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Cargi?
Anyone tried this yet? dropping reta for the last 3 weeks of prep and want something that will help with appetite?
Anyone tried this yet? dropping reta for the last 3 weeks of prep and want something that will help with appetite?
Been Using Reta for most of prep, Just went down to 1 mg from 4.5, and ive been extremely tired. Anyone know why that might be?
NEW MOTS-c Study | University of Copenhagen Published in Free Radical Biology and Medicine, researchers ran both transgenic mouse experiments and a human exercise trial to examine what MOTS-c actually does inside mitochondria — not just systemic metabolic effects. Key findings: • MOTS-c improved mitochondrial bioenergetic performance via PGC-1α and AMPK pathways • Effects occurred WITHOUT increasing mitochondrial protein content — meaning it makes existing mitochondria run more efficiently, not just builds more • Significantly reduced mitochondrial ROS emission and oxidative stress/protein damage • RNA-seq data showed improvements across redox handling, mitochondrial integrity, and OXPHOS efficiency Human component: Elevated interstitial MOTS-c during exercise showed no arterio-venous difference in skeletal muscle — suggesting muscle may NOT be the primary source of circulating MOTS-c during exercise. Bottom line: MOTS-c appears to optimize mitochondrial quality and efficiency from the inside out, with meaningful antioxidant effects. Research purposes only. 📄 PubMed: 41520850
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