GHK-Cu

Research compound / Cosmeceutical

Also known as: Copper Peptide, Glycyl-L-histidyl-L-lysine:copper(II)

Skin & HairTopicalSubcutaneousMicroneedling

A naturally occurring copper tripeptide found in human plasma, saliva, and urine. Declines with age. Studied for skin rejuvenation, wound healing, and hair growth.

Molecular Weight403.9 Da
Half-Life (t½)~12 hours (topical), ~1 hour (injected)
SequenceGHK + Cu²⁺

Mechanism of Action

Stimulates collagen I, III, and V synthesis, upregulates glycosaminoglycans and decorin, promotes angiogenesis, and has antioxidant and anti-inflammatory effects.

Dosing Protocol

Topical: 1-2% cream applied daily. Injectable: 50-200 mcg subcutaneous near target area.

Open peptide calculator

Reconstitution

50mg vial + 2mL BAC water = 25mg/mL (25,000 mcg/mL). Use very small volumes.

Storage

Protect from light. Lyophilized: -20°C. Solutions: 2-8°C.

Side Effects

  • Skin irritation (topical)
  • Mild redness at injection site

Key Research Findings

  • Increased collagen production by 70% in skin studies
  • Stimulated hair follicle growth in alopecia models
  • Reduced skin inflammation markers

Latest Verified Lab Report

No lab reports available for GHK-Cu yet.

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Research Use Only

This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.