GHRP-6

Experimental

Also known as: Growth Hormone Releasing Peptide-6

Growth Hormone PeptidesSubcutaneousIntramuscular

A first-generation growth hormone secretagogue that stimulates GH release via the ghrelin receptor. Known for strongly increasing appetite.

Molecular Weight873.0 Da

Half-Life (t½)~15-60 minutes

SequenceHis-D-Trp-Ala-Trp-D-Phe-Lys-NH2

Mechanism of Action

Binds ghrelin/GHS-R1a receptor on pituitary somatotrophs. Also stimulates cortisol, prolactin, and ghrelin release. Strong appetite stimulation via hypothalamic ghrelin signaling.

Dosing Protocol

100-300 mcg subcutaneous 2-3x daily on empty stomach. Often combined with a GHRH peptide.

Open peptide calculator

Reconstitution

5mg vial + 2mL BAC water = 2500 mcg/mL.

Storage

Lyophilized: -20°C. Reconstituted: 2-8°C.

Side Effects

●Intense hunger
●Water retention
●Cortisol elevation
●Tingling/numbness

Key Research Findings

●Robust GH release within 15-30 minutes of injection
●Significant appetite stimulation (useful for underweight conditions)
●Cytoprotective effects on cardiac tissue post-ischemia

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