Humanin
Also known as: HN, HNG (S14G variant)
A mitochondria-derived peptide with cytoprotective effects. Protects against oxidative stress, apoptosis, and neurodegenerative processes. Declines with age.
Mechanism of Action
Binds IGFBP-3 and BAX to inhibit apoptosis. Activates STAT3 and ERK signaling for cell survival. Enhances mitochondrial function and reduces oxidative stress.
Dosing Protocol
HNG (potent analog): 1-4 mg subcutaneous daily. Research protocols vary.
Open peptide calculatorReconstitution
5mg vial + 2mL BAC water.
Storage
Lyophilized: -20°C. Reconstituted: 2-8°C.
Side Effects
- ●Generally well-tolerated in animal studies
- ●Limited human safety data
Key Research Findings
- ●Neuroprotective against Alzheimer's-associated amyloid-beta toxicity
- ●Improved glucose metabolism and insulin sensitivity
- ●Higher circulating levels correlate with longevity in centenarians
Latest Verified Lab Report
No lab reports available for Humanin yet.
Community-funded testing results will appear here.
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This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.