Kisspeptin-10

Investigational

Also known as: Metastin 45-54, KP-10

Sexual HealthSubcutaneousIntravenous

A hypothalamic neuropeptide that stimulates GnRH release, triggering LH and FSH secretion. Being studied for reproductive medicine and as a diagnostic tool.

Molecular Weight1302.5 Da

Half-Life (t½)~28 minutes

SequenceTyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2

Mechanism of Action

Binds KISS1R (GPR54) on GnRH neurons in the hypothalamus, triggering GnRH pulsatile release. Upstream regulator of the entire HPG axis.

Dosing Protocol

50-100 mcg subcutaneous or IV bolus. Research protocols vary widely.

Open peptide calculator

Reconstitution

5mg vial + 2mL BAC water = 2500 mcg/mL.

Storage

Lyophilized: -20°C. Reconstituted: 2-8°C.

Side Effects

●Headache
●Nausea
●Flushing
●Elevated LH (expected)

Key Research Findings

●Potent stimulator of LH release in both sexes
●Potential IVF trigger alternative to hCG
●Enhanced sexual arousal and brain limbic activation in fMRI studies

Latest Verified Lab Report

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