KPV
Also known as: Lys-Pro-Val, Alpha-MSH fragment
A C-terminal tripeptide fragment of alpha-MSH with potent anti-inflammatory properties. Being studied for gut inflammation, IBD, and skin conditions.
Mechanism of Action
Enters cells and directly inhibits NF-kB nuclear translocation, suppressing inflammatory cytokine production. Does not require melanocortin receptor binding for anti-inflammatory effect.
Dosing Protocol
Oral: 200-500 mcg daily (BPC capsules for gut). Subcutaneous: 100-500 mcg daily.
Open peptide calculatorReconstitution
Available as oral capsules or injectable. 5mg vial + 2mL BAC water.
Storage
Room temperature (capsules). Lyophilized: -20°C.
Side Effects
- ●Generally very well-tolerated
- ●Minimal reported side effects
Key Research Findings
- ●Reduced colonic inflammation in IBD animal models
- ●Direct NF-kB inhibition without receptor-dependent signaling
- ●Accelerated wound healing and reduced skin inflammation
Latest Verified Lab Report
No lab reports available for KPV yet.
Community-funded testing results will appear here.
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This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.