Melanotan II

FDA Approved

Also known as: MT-II, MT2

Skin & HairSubcutaneous

A synthetic melanocortin peptide analog that stimulates melanogenesis (tanning) and has secondary effects on sexual function and appetite.

Molecular Weight1024.2 Da
Half-Life (t½)~33 minutes (effects last days)
SequenceAc-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

Mechanism of Action

Non-selective melanocortin receptor agonist. Activates MC1R (melanogenesis/tanning), MC3R/MC4R (sexual function, appetite suppression).

Dosing Protocol

Loading: 250-500 mcg daily for 1-2 weeks with UV exposure. Maintenance: 500 mcg 1-2x/week.

Open peptide calculator

Reconstitution

10mg vial + 2mL BAC water = 5000 mcg/mL.

Storage

Lyophilized: -20°C. Reconstituted: 2-8°C. Protect from light.

Side Effects

  • Nausea (common initially)
  • Facial flushing
  • Darkened moles
  • Spontaneous erections

Key Research Findings

  • Significant melanogenesis induction in fair-skinned subjects
  • Appetite suppression observed in clinical studies
  • Potential photoprotective effects under investigation

Latest Verified Lab Report

No lab reports available for Melanotan II yet.

Community-funded testing results will appear here.

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Research Use Only

This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.