Pentosan Polysulfate
Also known as: PPS, Elmiron, Cartrophen
A semi-synthetic heparinoid compound used for interstitial cystitis and being studied for osteoarthritis. Provides glycosaminoglycan layer restoration and anti-inflammatory effects.
Mechanism of Action
Restores the glycosaminoglycan layer of the bladder epithelium. Anti-inflammatory, anti-coagulant, and fibrinolytic properties. Promotes cartilage matrix synthesis in joints.
Dosing Protocol
Oral: 100mg 3x daily (FDA dosing). Injectable: 3mg/kg subcutaneous twice weekly for osteoarthritis.
Open peptide calculatorReconstitution
Injectable: supplied pre-mixed. Oral: capsules.
Storage
Room temperature.
Side Effects
- ●GI upset
- ●Headache
- ●Hair loss (rare, oral)
- ●Rare maculopathy with long-term use
Key Research Findings
- ●FDA-approved for interstitial cystitis pain relief
- ●Improved joint function in osteoarthritis clinical trials (injectable)
- ●Promoted cartilage regeneration in animal models
Latest Verified Lab Report
No lab reports available for Pentosan Polysulfate yet.
Community-funded testing results will appear here.
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This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.