PT-141

FDA Approved

Also known as: Bremelanotide, Vyleesi

Sexual HealthSubcutaneous

A melanocortin receptor agonist FDA-approved for hypoactive sexual desire disorder. Works on the central nervous system rather than the vascular system.

Molecular Weight1025.2 Da
Half-Life (t½)~2.7 hours
SequenceAc-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Mechanism of Action

Activates MC3R and MC4R melanocortin receptors in the hypothalamus, stimulating sexual arousal pathways in the CNS.

Dosing Protocol

500-1500 mcg subcutaneous, 45 minutes before activity. Max once per 24 hours, max 8 doses/month.

Open peptide calculator

Reconstitution

10mg vial + 2mL BAC water = 5000 mcg/mL.

Storage

Lyophilized: -20°C. Reconstituted: 2-8°C.

Side Effects

  • Nausea (common)
  • Flushing
  • Headache
  • Skin darkening with repeated use

Key Research Findings

  • FDA-approved as Vyleesi for HSDD in premenopausal women
  • Effective in both male and female arousal in clinical trials
  • CNS-mediated mechanism unlike PDE5 inhibitors

Latest Verified Lab Report

No lab reports available for PT-141 yet.

Community-funded testing results will appear here.

Vendor Trust Leaderboard

For PT-141

Trust leaderboard coming soon.

Vendor rankings based on verified lab test results.

Active Deals

APR Health Solutions
15% OFF
A

15% off with code at checkout.

TheResearchStop
Shop Vendor
Ameano Peptides
10% OFF
A

10% off with code at checkout.

theresearchstop
Shop Vendor
Puratek Peptides
10% OFF
Puratek Peptides

10% off — discount applied automatically via referral link.

Mile High Compounds
10% OFF
M

10% off with code at checkout.

theresearchstop
Shop Vendor
Advertisement

Sponsored Ad Space

Advertise with us

Research Use Only

This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.