SS-31
Also known as: Elamipretide, Bendavia, MTP-131
A mitochondria-targeted tetrapeptide that concentrates 1000x in the inner mitochondrial membrane. Restores bioenergetics and reduces oxidative damage.
Mechanism of Action
Selectively binds cardiolipin on the inner mitochondrial membrane, stabilizing electron transport chain complexes, reducing ROS production, and optimizing ATP synthesis.
Dosing Protocol
0.25 mg/kg/hr IV infusion or 40mg subcutaneous daily in clinical trials.
Open peptide calculatorReconstitution
Research-grade: typically supplied in solution.
Storage
Refrigerate 2-8°C. Protect from light.
Side Effects
- ●Injection site reactions
- ●Headache
- ●Generally well-tolerated in trials
Key Research Findings
- ●Improved cardiac function in Barth Syndrome patients (Phase 3)
- ●Reversed age-related mitochondrial dysfunction in preclinical models
- ●Improved exercise tolerance in heart failure trials
Latest Verified Lab Report
No lab reports available for SS-31 yet.
Community-funded testing results will appear here.
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This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.