VIP
Also known as: Vasoactive Intestinal Peptide, Aviptadil
A 28-amino acid neuropeptide with potent anti-inflammatory, immunomodulatory, and vasodilatory properties. Being studied for CIRS, pulmonary conditions, and autoimmune diseases.
Mechanism of Action
Binds VPAC1/VPAC2 receptors, suppressing TNF-alpha, IL-6, and NF-kB pathways. Promotes regulatory T-cells, enhances surfactant production in lungs, and dilates blood vessels.
Dosing Protocol
Intranasal: 50 mcg per nostril 4x daily (Shoemaker CIRS protocol). IV: clinical trial doses vary.
Open peptide calculatorReconstitution
Typically supplied pre-mixed for intranasal use.
Storage
Refrigerate 2-8°C. Very sensitive to degradation.
Side Effects
- ●Nasal congestion
- ●Diarrhea
- ●Hypotension (IV)
- ●Flushing
Key Research Findings
- ●Improved pulmonary function in COVID-19 ARDS (Aviptadil trials)
- ●Reduced inflammatory markers in CIRS/mold illness protocols
- ●Neuroprotective effects in neurodegenerative disease models
Latest Verified Lab Report
No lab reports available for VIP yet.
Community-funded testing results will appear here.
Vendor Trust Leaderboard
Trust leaderboard coming soon.
Vendor rankings based on verified lab test results.
Research Use Only
This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.